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3D expansion of stem cells

Traditional pluripotent stem cells are grown as adherent cultures, with limited and expensive scalability.Accellta solves the scale-up and cost challenges of stem cell culturing using the Maxells™ and Singles solutions.
Maxells™ are stem cells cultured as cell clusters devoid of feeder cells without micro-carriers. Using dynamic bioreactors, Maxells™ provides a vastly cost-effective means to expand stem cells in customized quantities.
Maxells™ delivers unprecedented magnitude and quality. Based on proprietary protocols developed by Accellta, Maxells technology can be applied to create both research-grade as well as clinical-grade feeder-free xeno-free cultures. In addition, Accellta developed proprietary protocols for the differentiation of the Maxells directly in suspension to a variety of cell types (e. g., MSCs. HSCs, NPs, CMs)

  • Cell concentration: >20 million cells/ml
  • Expansion factor: X30-35 in 11 days
  • Suitable for undifferentiated pluripotent stem cells and progenitor cells
  • Does not require enzymatic splitting
  • Rock inhibitor-free, xeno-free defined medium
  • Medium easily refreshed every two-three days
  • Straightforward perfusion process in bioreactors
  • Easy transition from suspension culture back to adherent culture
  • Feeder cell-free
  • Homogenous exposure to medium’s nutrients
  • >95% of cells are pluripotent; <5% spontaneous differentiation
  • Karyotype stability
  • High viability rate
  • Methods for directed differentiation in suspension

Atlas of Human Pluripotent Stem Cells

978 1 61779 548 0


Michal Amit, Joseph Itskovitz-Eldor


Accelerating stem cell technologies

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